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Pancreatic Cancer

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Pancreatic Cancer signs, follow-up guidance, risk factors, testing information, and trusted cancer resources from PINC Foundation.

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Pancreatic cancer can be difficult to find early because symptoms may be subtle. Jaundice, unexplained weight loss, or persistent upper-abdominal/back pain needs follow-up. Pancreatic cancer is rare in young adults. When it occurs younger, inherited risk can be more relevant. A strong family pattern deserves genetic counseling even without symptoms.
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• Smoking • Chronic pancreatitis • Long-standing diabetes and excess body weight • Family history and inherited variants such as BRCA2, PALB2, or CDKN2A • Increasing age
• Smoking • Chronic pancreatitis • Long-standing diabetes and excess body weight • Family history and inherited variants such as BRCA2, PALB2, or CDKN2A • Increasing age
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• Yellow skin or eyes, dark urine, pale or greasy stools, or itching • Upper-abdominal pain that may spread to the back • Unexplained weight loss or loss of appetite • Nausea, vomiting, or new digestive difficulty • New diabetes or diabetes that suddenly becomes harder to control Jaundice should be assessed promptly. Seek urgent care for severe pain, repeated vomiting, fever with jaundice, confusion, or fainting.
• Yellow skin or eyes, dark urine, pale or greasy stools, or itching • Upper-abdominal pain that may spread to the back • Unexplained weight loss or loss of appetite • Nausea, vomiting, or new digestive difficulty • New diabetes or diabetes that suddenly becomes harder to control Jaundice should be assessed promptly. Seek urgent care for severe pain, repeated vomiting, fever with jaundice, confusion, or fainting.
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There is no routine pancreatic cancer screening for average-risk people. Selected high-risk individuals with strong family history or certain inherited variants may be offered MRI and/or endoscopic ultrasound in an expert surveillance program. • Blood tests, including liver tests • Pancreas-protocol CT or MRI/MRCP • Endoscopic ultrasound • Biopsy when tissue confirmation is needed • Genetic and tumor biomarker testing when cancer is diagnosed
There is no routine pancreatic cancer screening for average-risk people. Selected high-risk individuals with strong family history or certain inherited variants may be offered MRI and/or endoscopic ultrasound in an expert surveillance program. • Blood tests, including liver tests • Pancreas-protocol CT or MRI/MRCP • Endoscopic ultrasound • Biopsy when tissue confirmation is needed • Genetic and tumor biomarker testing when cancer is diagnosed
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• Could these symptoms reflect bile duct blockage? • Do I need pancreas-specific CT, MRI, or endoscopic ultrasound? • Does my family history qualify me for genetic counseling? • Should testing occur at a high-volume pancreas center?
• Could these symptoms reflect bile duct blockage? • Do I need pancreas-specific CT, MRI, or endoscopic ultrasound? • Does my family history qualify me for genetic counseling? • Should testing occur at a high-volume pancreas center?
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
https://www.cancer.gov/types/pancreatic https://www.cancer.org/cancer/types/pancreatic-cancer.html
https://www.cancer.gov/types/pancreatic https://www.cancer.org/cancer/types/pancreatic-cancer.html
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